Sandimmun 25mg Capsule contains Cyclosporine as its active ingredient. It is a medication used to prevent organ rejection in transplant patients and to treat various autoimmune conditions. Cyclosporine works by suppressing the immune system, thereby preventing the body from attacking transplanted organs or tissues.
Cyclosporine: Cyclosporine is an immunosuppressive agent that inhibits the activity of T-lymphocytes, a type of white blood cell involved in immune responses. By suppressing T-cell function, Cyclosporine helps prevent rejection of transplanted organs and reduces inflammation in autoimmune diseases.
Sandimmun 25mg Capsule is indicated for the following conditions:
Prevention of organ rejection in patients who have undergone kidney, liver, or heart transplantation.
Treatment of certain autoimmune conditions, such as severe psoriasis, rheumatoid arthritis, and atopic dermatitis.
Mechanism of Action:
Cyclosporine exerts its immunosuppressive effects by selectively inhibiting the activation of T-lymphocytes, which play a key role in the immune response. By blocking the production of cytokines and other signaling molecules involved in immune activation, Cyclosporine reduces inflammation and prevents the immune system from attacking transplanted organs or tissues.
Sandimmun 25mg Capsule is taken orally, usually once or twice daily, as directed by a healthcare professional. The dosage may vary depending on the patient’s medical condition, kidney function, and response to treatment. It is important to take the medication consistently and at the same time each day to maintain stable blood levels.
Common side effects of Sandimmun 25mg Capsule may include:
Increased susceptibility to infections
High blood pressure
Gastrointestinal disturbances (such as nausea, vomiting, diarrhea)
Regular monitoring of kidney function, blood pressure, and blood levels of Cyclosporine is essential during treatment.
Avoid exposure to sunlight and ultraviolet (UV) light, as Cyclosporine may increase the risk of skin cancer and other skin conditions.
Inform healthcare providers about all current medications, including over-the-counter drugs and supplements, as they may interact with Cyclosporine.
Avoid consumption of grapefruit or grapefruit juice, as it may increase blood levels of Cyclosporine.
Sandimmun 25mg Capsule is contraindicated in patients with:
Hypersensitivity to Cyclosporine or any component of the formulation.
Severe kidney impairment.
Active untreated infections.
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