Uperio Fct 100mg Tablet

Uperio Fct 100mg Tablet is a medication that contains a combination of Sacubitril & Valsartan as its active ingredients. It is prescribed for the treatment of heart failure with reduced ejection fraction (HFrEF) in adult patients. This combination medication works by enhancing the effects of natriuretic peptides and blocking the angiotensin II receptor, leading to vasodilation, improved cardiac function, and reduced risk of cardiovascular events.

Active Ingredients:

1. Sacubitril: Sacubitril is a neprilysin inhibitor that enhances the effects of natriuretic peptides, such as atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP). These peptides promote vasodilation, diuresis, and natriuresis, which helps to improve heart function and reduce fluid retention.
2. Valsartan: Valsartan is an angiotensin II receptor blocker (ARB) that blocks the action of angiotensin II, a hormone that causes vasoconstriction and increases blood pressure. By blocking the angiotensin II receptor, valsartan causes vasodilation, decreases blood pressure, and reduces the workload on the heart.

Uses:

Uperio Fct 100mg Tablet is indicated for the treatment of:

• Heart failure with reduced ejection fraction (HFrEF) in adult patients to reduce the risk of cardiovascular death and hospitalization for heart failure.

Mechanism of Action:

The combination of Sacubitril and Valsartan in Uperio Fct Tablet works synergistically to:

• Enhance the effects of natriuretic peptides, leading to vasodilation, diuresis, and natriuresis, which helps to improve heart function and reduce fluid retention.
• Block the angiotensin II receptor, resulting in vasodilation, decreased blood pressure, and reduced workload on the heart.

Administration:

Uperio Fct 100mg Tablet is taken orally, usually once or twice daily with or without food, as directed by a healthcare professional. The dosage may be adjusted based on individual patient response and tolerability.

Side Effects:

Common side effects of Uperio Fct 100mg Tablet may include:

• Hypotension (low blood pressure)
• Hyperkalemia (high potassium levels)
• Renal impairment
• Dizziness
• Cough
• Fatigue

Precautions:

• Monitor blood pressure, renal function, and electrolyte levels regularly during treatment with Uperio Fct Tablet.
• Use caution in patients with a history of angioedema, renal impairment, or hyperkalemia.
• Avoid concomitant use of potassium-sparing diuretics, potassium supplements, or other medications that increase potassium levels.
• Inform healthcare providers about all current medications, including over-the-counter drugs and supplements, before starting Uperio Fct Tablet.

Contraindications:

Uperio Fct 100mg Tablet is contraindicated in patients with a history of angioedema related to previous angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) therapy. It should not be used during pregnancy or breastfeeding.