Glempa M 5mg/500mg Tablet

Glempa M 5mg/500mg Tablet contains two active ingredients: Empagliflozin & Metformin hydrochloride (HCI). Empagliflozin is classified as a sodium-glucose co-transporter 2 (SGLT2) inhibitor, while metformin HCI is a biguanide antidiabetic medication. This combination medication is prescribed for the treatment of type 2 diabetes mellitus.

Active Ingredients:

• Empagliflozin: This SGLT2 inhibitor reduces blood sugar levels by inhibiting the reabsorption of glucose in the kidneys, leading to increased urinary excretion of glucose.
• Metformin HCI: A biguanide antidiabetic drug, metformin HCI lowers blood sugar levels by decreasing hepatic glucose production, reducing intestinal absorption of glucose, and improving insulin sensitivity.

Uses:

Glempa M Tablet is indicated for managing type 2 diabetes mellitus in adults. It helps improve glycemic control by lowering blood sugar levels through different mechanisms: empagliflozin promotes urinary glucose excretion, while metformin HCI reduces hepatic glucose production and enhances insulin sensitivity.

Mechanism of Action:

• Empagliflozin: Inhibits sodium-glucose co-transporter 2 (SGLT2) in the kidneys, thereby reducing glucose reabsorption from the tubular lumen and increasing urinary glucose excretion.
• Metformin HCI: Decreases hepatic glucose production, inhibits gluconeogenesis, reduces intestinal absorption of glucose, and enhances peripheral glucose uptake and utilization by improving insulin sensitivity.

Administration:

Glempa M Tablet is typically taken orally with meals as directed by a healthcare professional. The dosage may vary depending on individual response and other factors. Patients should follow the dosage instructions provided by their healthcare provider.

Side Effects:

Common side effects of Glempa M Tablet may include:

• Hypoglycemia (low blood sugar)
• Genital yeast infections
• Urinary tract infections
• Increased urination
• Thirst
• Nausea
• Diarrhea
• Abdominal pain

Precautions:

Before using Glempa M Tablet, patients should consider the following precautions:

• Inform healthcare providers of any known allergies to empagliflozin, metformin HCI, or other medications.
• Regularly monitor blood sugar levels, especially during initial treatment or dosage adjustments.
• Use caution in patients with kidney problems, dehydration, or hypotension.
• Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis.
• Inform healthcare providers of any other medications, supplements, or herbal products being taken, as they may interact with empagliflozin or metformin HCI.