Glempa M 5mg/500mg Tablet contains two active ingredients: Empagliflozin & Metformin hydrochloride (HCI). Empagliflozin is classified as a sodium-glucose co-transporter 2 (SGLT2) inhibitor, while metformin HCI is a biguanide antidiabetic medication. This combination medication is prescribed for the treatment of type 2 diabetes mellitus.
Empagliflozin: This SGLT2 inhibitor reduces blood sugar levels by inhibiting the reabsorption of glucose in the kidneys, leading to increased urinary excretion of glucose.
Metformin HCI: A biguanide antidiabetic drug, metformin HCI lowers blood sugar levels by decreasing hepatic glucose production, reducing intestinal absorption of glucose, and improving insulin sensitivity.
Glempa M Tablet is indicated for managing type 2 diabetes mellitus in adults. It helps improve glycemic control by lowering blood sugar levels through different mechanisms: empagliflozin promotes urinary glucose excretion, while metformin HCI reduces hepatic glucose production and enhances insulin sensitivity.
Mechanism of Action:
Empagliflozin: Inhibits sodium-glucose co-transporter 2 (SGLT2) in the kidneys, thereby reducing glucose reabsorption from the tubular lumen and increasing urinary glucose excretion.
Metformin HCI: Decreases hepatic glucose production, inhibits gluconeogenesis, reduces intestinal absorption of glucose, and enhances peripheral glucose uptake and utilization by improving insulin sensitivity.
Glempa M Tablet is typically taken orally with meals as directed by a healthcare professional. The dosage may vary depending on individual response and other factors. Patients should follow the dosage instructions provided by their healthcare provider.
Common side effects of Glempa M Tablet may include:
Hypoglycemia (low blood sugar)
Genital yeast infections
Urinary tract infections
Before using Glempa M Tablet, patients should consider the following precautions:
Inform healthcare providers of any known allergies to empagliflozin, metformin HCI, or other medications.
Regularly monitor blood sugar levels, especially during initial treatment or dosage adjustments.
Use caution in patients with kidney problems, dehydration, or hypotension.
Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis.
Inform healthcare providers of any other medications, supplements, or herbal products being taken, as they may interact with empagliflozin or metformin HCI.
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