Glempa M 5/850mg Tablet

Glempa M 5/850mg Tablet combines two active ingredients: empagliflozin and metformin hydrochloride (HCI). Empagliflozin belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors, while metformin HCI is a biguanide antidiabetic medication. This combination medication is used for the treatment of type 2 diabetes mellitus.

Active Ingredients:

• Empagliflozin: Empagliflozin is an SGLT2 inhibitor that works by inhibiting the reabsorption of glucose in the kidneys, leading to increased urinary excretion of glucose and reduced blood sugar levels.
• Metformin HCI: Metformin is a biguanide antidiabetic medication that reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by enhancing peripheral glucose uptake and utilization.

Uses:

Glempa M Tablet is indicated for the management of type 2 diabetes mellitus in adults. It helps to improve glycemic control by lowering blood sugar levels through different mechanisms of action: empagliflozin by promoting urinary glucose excretion and metformin HCI by reducing hepatic glucose production and improving insulin sensitivity.

Mechanism of Action:

• Empagliflozin: Inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules, thereby reducing the reabsorption of filtered glucose from the tubular lumen and increasing urinary glucose excretion.
• Metformin HCI: Reduces hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis, decreases intestinal absorption of glucose, and enhances peripheral glucose uptake and utilization by improving insulin sensitivity.

Administration:

Glempa M Tablet is typically taken orally with meals, as directed by the healthcare provider. The dosage may vary depending on the patient’s individual response to treatment and other factors. It is important to follow the dosage instructions provided by the healthcare provider.

Side Effects:

Common side effects associated with Glempa M Tablet may include:

• Hypoglycemia (low blood sugar)
• Genital yeast infections
• Urinary tract infections
• Increased urination
• Thirst
• Nausea
• Diarrhea
• Abdominal pain

Precautions:

Before using Glempa M Tablet, patients should consider the following precautions:

• Inform healthcare providers of any known allergies to empagliflozin, metformin HCI, or other medications.
• Monitor blood sugar levels regularly, especially during the initial stages of treatment or when changes are made to the dosage.
• Use with caution in patients with a history of kidney problems, dehydration, or hypotension.
• Avoid excessive alcohol consumption while taking Glempa M Tablet, as it may increase the risk of lactic acidosis.
• Inform healthcare providers of any other medications, supplements, or herbal products being taken, as they may interact with empagliflozin or metformin HCI.