Sita-Met XR 50/500mg tablet

Sita-Met XR 50/500mg tablet is a combination oral medication that merges two antihyperglycemic agents, Sitagliptin and Metformin Hydrochloride Extended-Release, specifically designed for the management of type 2 diabetes mellitus. This medication is formulated to improve glycemic control in adults with type 2 diabetes mellitus as part of a comprehensive treatment approach that includes diet and exercise.

Uses:

Sita-Met XR is utilized in the treatment of type 2 diabetes mellitus, particularly in individuals for whom diet and exercise alone do not suffice to control blood sugar levels. The medication serves the following purposes:

• Enhances Glycemic Control: It helps in lowering blood sugar levels, thereby assisting in the effective management of type 2 diabetes.
• Combination Therapy: Ideal for patients not adequately controlled on metformin or sitagliptin alone, or in those already treated with the combination of sitagliptin and metformin as separate tablets.

How it Works:

• Metformin works by decreasing glucose production in the liver, decreasing glucose absorption in the intestines, and improving insulin sensitivity, which enhances peripheral glucose uptake and utilization.
• Sitagliptin works by regulating the levels of insulin your body produces after eating. It does this by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, which results in increased levels of incretin hormones. These hormones help to increase insulin synthesis and release in a glucose-dependent manner and decrease the levels of glucagon in the bloodstream.

Side Effects:

While taking Sita-Met XR, some individuals may experience side effects, although not everyone gets them. Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite

Rare but serious side effects can include lactic acidosis, a build-up of lactic acid in the blood, which is a medical emergency. Symptoms of lactic acidosis include feeling very weak, tired, or uncomfortable; unusual muscle pain; trouble breathing; unusual or unexpected stomach discomfort; feeling cold; feeling dizzy or lightheaded; or suddenly developing a slow or irregular heartbeat.

Precautions:

Before taking Sita-Met XR, inform your healthcare provider if you have any kidney or liver problems, heart problems, or if you are pregnant or planning to become pregnant. The use of metformin may need to be assessed or adjusted in these conditions.

When Not to Use:

• Individuals with renal impairment or a history of hypersensitivity to sitagliptin, metformin, or any other component of the product should not use Sita-Met XR.
• It is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis.

FAQ:

1. Can Sita-Met XR be used with insulin?
   • Yes, it can be used in combination with insulin to improve glycemic control. However, this should be under the guidance of a healthcare professional.
2. Should I take Sita-Met XR with food?
   • Yes, taking it with meals can help reduce the gastrointestinal side effects associated with metformin.
3. What if I miss a dose of Sita-Met XR?
   • If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at one time.
4. Can I stop taking Sita-Met XR if my blood sugar levels are under control?
   • You should not stop taking Sita-Met XR without discussing it with your healthcare provider, even if your blood sugar levels are under control.
5. How should I store Sita-Met XR?
   • Store it at room temperature, away from direct light and moisture, and keep it out of reach of children.