Sitazan 50/500mg Tablet is a combination medication containing two active ingredients: Sitagliptin & Metformin. Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, while Metformin belongs to the biguanide class of antidiabetic medications. This combination is used to manage type 2 diabetes mellitus by improving blood sugar control.
Uses:
Sitazan 50/500mg Tablet is indicated for:
- Type 2 Diabetes Mellitus: Used to improve glycemic control in adults with type 2 diabetes mellitus, particularly when blood sugar levels are not adequately controlled by diet and exercise alone.
- Dual Mechanism of Action: Sitagliptin works by increasing the levels of incretin hormones, which stimulate insulin release and decrease glucagon secretion, while Metformin improves insulin sensitivity and decreases hepatic glucose production.
Side Effects:
While generally well-tolerated, Sitazan 50/500mg Tablet may lead to some side effects, including:
- Gastrointestinal disturbances (such as diarrhea, nausea, vomiting, or abdominal discomfort).
- Hypoglycemia (low blood sugar), particularly when used with other antidiabetic medications.
- Headache.
- Upper respiratory tract infection.
- Rarely, allergic reactions or lactic acidosis may occur with metformin use.
Precautions:
Before using Sitazan 50/500mg Tablet, it’s essential to consider the following precautions:
- Kidney Function: Use with caution in patients with impaired kidney function, as metformin is excreted by the kidneys. Regular monitoring of kidney function is recommended.
- Liver Function: Monitor liver function tests regularly, as metformin may rarely cause liver dysfunction or hepatitis.
- Hypoglycemia: Monitor blood sugar levels regularly, especially during concurrent use with other antidiabetic medications.
- Pregnancy and Breastfeeding: Use under medical supervision during pregnancy or breastfeeding, as the safety of Sitazan 50/500mg Tablet in pregnant or nursing women has not been established.
When Not to Use:
Avoid using Sitazan 50/500mg Tablet if you:
- Have severe kidney impairment (eGFR less than 30 mL/min/1.73 m²) or a history of lactic acidosis.
- Are allergic to sitagliptin, metformin, or any other ingredients in the tablet.
- Have type 1 diabetes mellitus or diabetic ketoacidosis.
FAQs:
- How should I take Sitazan 50/500mg Tablet?
- Take as directed by your healthcare provider. Swallow the tablet whole with a glass of water, preferably with meals to reduce gastrointestinal side effects.
- Can Sitazan 50/500mg Tablet be used alone or with other antidiabetic medications?
- Sitazan Tablet can be used alone or in combination with other antidiabetic medications, depending on the individual’s blood sugar control and treatment regimen.
- What should I do if I miss a dose of Sitazan 50/500mg Tablet?
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
- Are there any dietary restrictions while taking Sitazan 50/500mg Tablet?
- Maintain a balanced diet and follow your healthcare provider’s dietary recommendations for diabetes management while taking Sitazan Tablet.
- Can Sitazan 50/500mg Tablet cause weight gain?
- Metformin, one of the components of Sitazan Tablet, is associated with modest weight loss or weight neutrality in most patients. However, individual responses may vary.
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