SACUBITRIL is a medication that belongs to a class of drugs called angiotensin receptor-neprilysin inhibitors (ARNI). It is used to treat heart failure in adults. The drug works by blocking the action of certain hormones that constrict blood vessels and increase blood pressure, while also increasing the levels of a substance called natriuretic peptides, which help to relax blood vessels and reduce blood pressure.

Benefits:

• Improves symptoms of heart failure, such as shortness of breath and fatigue

• Reduces the risk of hospitalization for heart failure

• May improve overall survival in people with heart failure

Side Effects:

• Headache

• Dizziness

• Cough

• Diarrhea

• Nausea

• Vomiting

• Abdominal pain

• Angioedema (swelling of the face, lips, tongue, or throat)

• Chest pain

• Rapid or irregular heartbeat

It’s important to note that not all people will experience side effects and most of the side effects are mild and temporary. Consult with your healthcare provider if you have any concerns or experience any severe side effects.