Glytec M Xr 50/1000mg Tablet is a combination medication containing two active ingredients: Sitagliptin & Metformin. Sitagliptin is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, while metformin is a biguanide antidiabetic agent. This combination is used to manage type 2 diabetes mellitus by helping to regulate blood sugar levels.
Sitagliptin: Sitagliptin works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which leads to increased levels of incretin hormones. These hormones help regulate blood sugar levels by stimulating insulin secretion and inhibiting glucagon release.
Metformin: Metformin primarily decreases glucose production in the liver and enhances insulin sensitivity in peripheral tissues such as muscle and fat cells. It also improves glucose utilization by these tissues.
Glytec M XR Tablet is prescribed for the management of type 2 diabetes mellitus in adults. It helps control blood sugar levels by:
Stimulating insulin secretion
Decreasing hepatic glucose production
Increasing peripheral glucose uptake
Mechanism of Action:
The combination of sitagliptin and metformin works synergistically to improve glycemic control in patients with type 2 diabetes mellitus. Sitagliptin increases incretin hormone levels, leading to enhanced insulin secretion and reduced glucagon release. Metformin decreases hepatic glucose production and enhances peripheral glucose utilization, resulting in improved blood sugar levels.
Glytec M XR Tablet is typically taken orally with meals to reduce gastrointestinal side effects. The dosage and frequency of administration may vary depending on the patient’s condition and response to treatment. It is essential to follow the dosage instructions provided by the healthcare provider.
Common side effects associated with Glytec M XR Tablet may include:
Hypoglycemia (low blood sugar), especially when used in combination with other antidiabetic medications
Before taking Glytec M XR Tablet, patients should consider the following precautions:
Inform healthcare providers about any known allergies to sitagliptin, metformin, or other medications.
Monitor blood sugar levels regularly, especially during the initial stages of treatment or when changes are made to the dosage.
Use caution in patients with kidney impairment, as metformin can accumulate and increase the risk of lactic acidosis.
Avoid excessive alcohol consumption while taking Glytec M XR Tablet, as it may potentiate the risk of lactic acidosis.
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